Web10 Jul 2024 · In this phase III multicenter randomized controlled trial, patients were stratified by dose (45 v 50.4 Gy), use of chemotherapy (yes v no), and disease site (cervix v endometrium), then randomly assigned 1:1 to receive either standard four-field pelvic RT or pelvic IMRT. 11 Patients were treated to 45 Gy or 50.4 Gy on the basis of physician … Webthe CCRN for future trial development and to better un-derstand the challenges of clinical trial enrollment in LMIC. The presymposium survey (presurvey) was sent to all ... the Sedlis criteria12,15 or for positive nodes, positive mar-gins, or parametrial involvement.3,12 Almost all centers surveyed had RT available, although it is important to ...
A phase III randomized trial of postoperative pelvic ... - PubMed
Web17 Apr 2024 · PURPOSE The primary objective was to determine if vaginal cuff brachytherapy and chemotherapy (VCB/C) increases recurrence-free survival (RFS) … Web30 Jun 2024 · The Sedlis criteria define risk factors for recurrence warranting post-hysterectomy radiation for early-stage cervical cancer; however, these factors were … thala lodge
Role of adjuvant therapy after radical hysterectomy in intermediate …
WebObjective. To compare stages IB1 and IB2 cervical cancers treated with radical hysterectomy (RH) and to define predictors of nodal status and recurrence. Methods. Patients with stage IB cervical cancers undergoing RH between 1990 and 2000 were evaluated and clinicopathological variables were abstracted. The perioperative complication rate, … Web15 Dec 2009 · Health status and quality of life in patients with stable coronary artery disease and chronic kidney disease treated with optimal medical therapy or percutaneous … WebIn the GOG trial published by Sedlis et al. in 1999, the criteria for adjuvant radiotherapy were defined for squamous cell carcinoma at an estimated recurrence risk of at least 30%, which is a very high threshold . More recently, an ancillary analysis of GOG 49, 92, and 141 trials was conducted to better identify the risk of relapse according to tumor histopathological … thalamabele