Florence imrt trial

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August undefined, 2024

WebFeb 11, 2024 · ORCID: 0000–0001-6019–7309. In the treatment of breast cancer, intensity-modulated radiation therapy (IMRT) reportedly reduces the high-dose irradiation of at-risk organs and decreases the ... Webexplained the study’s lead author, Icro Meattini, MD, of the University of Florence in Italy. In recent years, researchers have sought to determine whether APBI might be as effective …

Accelerated Partial-Breast Irradiation Compared With …

WebOct 1, 2024 · Ten years results of the Canadian breast intensity modulated radiation therapy (IMRT) randomized controlled trial. Radiother Oncol, 121 (2016), pp. 414-419. Article. ... Long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol, 38 (2024), pp. 4175-4183. WebA Phase II Randomized Trial of Proton vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients with IDH Mutant, Low to Intermediate Grade Gliomas. Goal: To compare if proton beam radiation therapy is more effective than photon-based beam intensity-modulated radiation therapy in treating patients with glioma. highlight 37075

The impact of age on early breast cancer after breast conserving ...

WebMar 9, 2024 · Mayo Clinic doctors use the latest imaging techniques to carefully plan radiation treatments. Doctors use CT scans, MRI scans and positron emission tomography scans, also called PET scans, to create a treatment plan that targets just the cancer. Proton beam therapy facilities at Mayo Clinic use intensity-modulated pencil beam scanning. WebMar 28, 2024 · It is worth noting that ultra-fractionated EBRT options have also been increasingly adopted following the publication of the APBI-Florence-IMRT trial that demonstrated equivalent local control and survival of a 5-fraction partial-breast EBRT regimen compared to conventional whole-breast irradiation (21). In this trial, the five … WebApr 7, 2014 · Lorenzo Livi, Full Professor; Chief Radiotherapy-Oncology Unit; Florence University, Azienda Ospedaliero-Universitaria Careggi: ClinicalTrials.gov Identifier: … small mobility

Patient-Reported Toxicity During Pelvic Intensity …

Accelerated Partial-Breast Irradiation Compared With Whole-Breast

WebAug 24, 2024 · The Florence trial showed equivalent outcomes for WBI (50 Gy in 25 fractions with tumor bed boost) vs. APBI (30 Gy in five every-other-day fractions) using IMRT. WebThe APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective partial breast … highlight 33 restaurantWebJul 10, 2024 · From 2012 to 2015, 289 patients were enrolled, of whom 278 were eligible. Between baseline and end of RT, the mean EPIC bowel score declined 23.6 points in the standard RT group and 18.6 points in the … highlight 33 perth

"WebJun 1, 2024 · The APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective partial breast irradiation schedule, with long-term … " - Florence imrt trial

Florence imrt trial

WebAPBI-IMRT-Florence trial Delivery technique In the original protocol (NCT02104895), ﬁve 6-MV step-and-shoot IMRT coplanar ﬁelds were used.10 A dose of 30 Gy in 5 nonconsecutive, once-daily fractions was prescribed. At the time of the study design, the every-other-day approach was chosen to be cautious in regard to the toxicity proﬁle. WebFeb 15, 2024 · Abstract. Background. Partial breast irradiation (PBI) is a reasonable alternative for a whole breast irradiation (WBI) in selected early stage breast cancer patients. The 5-year analysis of the APBI IMRT Florence phase 3 trial showed no significant difference in terms of ipsilateral tumor recurrence (IBTR) and survival rates between the …

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WebJan 1, 2024 · The APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective … WebDec 15, 2024 · APBI-IMRT Florence Trial Primary endpoint: Ipsilateral breast tumor recurrence Median follow up: 10.7 years Meattiniet al., JCO 2024 520 patients enrolled 30 Gy in 5 fxQOD PBI, 1.5 weeks (n=260) 50Gy in 25 fx WBI, 5 weeks (n=260) 47 Toxicity Reduction in Breast Cancer APBI-IMRT Florence Trial Efficacy Meattiniet al., JCO 2024 48

WebOct 17, 2024 · To date, only the Florence IMRT-APBI phase 3 trial reported the outcomes of exclusive IMRT accelerated PBI compared to WBI, demonstrating no significant difference between the two groups in terms of ipsilateral breast tumor recurrences (IBTR). The PBI group presented significantly better results considering acute (p=0.0001), late (p=0.004), … WebMar 1, 2015 · Methods. This study was performed at the University of Florence (Florence, Italy). Women aged more than 40 years affected by early BC, with a maximum pathological tumour size of 25 mm, were randomly assigned in a 1:1 ratio to receive either WBI or APBI using IMRT.Patients in the APBI arm received a total dose of 30 Gy to the tumour bed in …

WebJun 1, 2010 · Purpose: To evaluate with a randomized clinical trial the possibility of treating the index quadrant with external intensity-modulated radiotherapy (IMRT) in a selected group of patients with early-stage breast cancer and to analyze the acute toxicity. Methods and materials: From September 2005, a randomized Phase III clinical trial has been …

WebDec 11, 2024 · A fourth study, the Florence trial, 13 used the QLQ-BR23 subscale, but only at baseline and 2 years after completion of treatment. Patients were randomly assigned to partial-breast IMRT using 30 Gy in …

WebMay 25, 2024 · 566 Background: The impact of age on local recurrence rate of patients affected by early breast cancer is still unclear. The standard of care for older adult largely varies depending on patient- and tumor-related features, but also on national guidelines. We recently presented the 10 years median follow update of the APBI-IMRT Florence phase … small mod minecraftWebAug 24, 2024 · PURPOSE To report the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) Florence … small mod minecraft pcWebMar 9, 2024 · Mayo Clinic doctors use the latest imaging techniques to carefully plan radiation treatments. Doctors use CT scans, MRI scans and positron emission … highlight 4 cornelsenWebMay 13, 2024 · Ten years results of the Canadian breast intensity modulated radiation therapy (IMRT) randomized controlled trial. Radiother Oncol 2016; 121:414–419. [Google Scholar] 19. Patel ... Long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol 2024; 38:4175–4183. highlight 4-rollen kabinentrolley 55 cmWebJan 28, 2024 · The Florence IMRT trial which delivered EB-APBI with 5 fractions of 6 Gy every other day showed similar results to conventionally fractionated whole-breast … highlight 1982WebAug 2, 2024 · Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet. 2024 Sep 9;390(10099):1048-1060. doi: 10.1016/S0140-6736(17)31145-5. Epub 2024 Aug 2. small model homes i the philippinesWebAug 30, 2024 · who randomized patients to intensity modulated radiation therapy (IMRT) APBI (30 Gy in 5 nonconsecutive daily fractions) versus conventionally fractionated WBI. … highlight 4th one day