WebCyclophosphamide 1.5 to 2 mg/kg orally once a day is usually given and may particularly benefit antineutrophil cytoplasmic antibody (ANCA)–positive patients; monthly pulse regimens may cause fewer adverse effects (eg, … WebSep 12, 2024 · We prefer cyclophosphamide, rather than chlorambucil, because it is associated with fewer adverse effects. In patients who wish to avoid cytotoxic therapy, treatment with rituximab may be a reasonable alternative. ... (GN), acute hypersensitivity interstitial nephritis, or acute bilateral renal vein thrombosis. ...
Cyclophosphamide pulmonary toxicity - UpToDate
WebSep 18, 2024 · Hypersensitivity. Uncommon (0.1% to 1%): Hypersensitivity reaction, anaphylactic/anaphylactoid reaction. Very rare (less than 0.01%): Anaphylactic shock . … WebFeb 17, 2024 · Cyclophosphamide is an alkylating agent that prevents cell division by cross-linking DNA strands and decreasing DNA synthesis. It is a cell cycle phase nonspecific agent. Cyclophosphamide also possesses potent immunosuppressive activity. Cyclophosphamide is a prodrug that must be metabolized to active metabolites in the … digital factory v10 setup
reversible cause of acute renal failure Postgraduate Medical …
WebAug 21, 2024 · Cyclophosphamide is a nitrogen mustard alkylator employed in the treatment of many malignancies and autoimmune disorders. Despite reports of … WebFeb 23, 2024 · Cytoxan ( cyclophosphamide ) is an orally administered prescription medication pill used to treat a variety of cancers, such as Hodgkin's lymphoma (Hodgkin's disease), non-Hodgkin's lymphoma (NHL), multiple myeloma (MM), leukemia, and breast carcinoma. Cytoxan is also used for the treatment of pediatric nephrotic syndrome. 1 WebJul 4, 2024 · NCBI Bookshelf digital fairways scam